The overlap between the FimH pocket residues and mAb926 and mAb475 epitopes.

Distances between mannose ligand and hydrogen bond forming FimH amino acids in the active and inactive conformation of the binding pocket are also shown.
1 Distance between hydrogen bond forming atoms of α-D-mannose and FimH amino acid residues in the active- (1UWF) and the inactive (3JWN) conformers of lectin domain as measured by PyMole.
*AA involved in hydrophobic interactions with mannose.
The overlap between the FimH pocket residues and mAb926 and mAb475 epitopes.