Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib
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Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib Descriptor: 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine, ALK TYROSINE KINASE RECEPTOR Authors: McTigue, M, Deng, Y, Liu, W, Brooun, A, Stewart, A. Deposit date: 2015-07-23 Release date: 2016-06-08 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Resensitization to Crizotinib by the Lorlatinib Alk Resistance Mutation L1198F. N.Engl.J.Med., 374, 2016
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2015-07-23
