Types of models used to summarize profiles.

The number (proportion) of profiles modelled with each model selected by our proposed LMMS approach. Models are abbreviated as linear (LIN), spline (SPL), subject-specific intercept (SSI), and subject-specific intercept and slope (SSIS). Models were applied to cell line breast cancer data (Cell), Saccharomyces paradoxus evolution data (Yeast), Mus musculus chemotherapy data (Mouse), and Homo Sapiens kidney rejection Non-Rejection (NR) data (Human). The row ‘Removed’ indicates the percentage of filtered profiles using the 2-cluster model-based clustering on RT and RI.