Dpo4 DNA polymerase (R336A) in complex with DNA containing an 8oxoG template lesion

NIAID Data Ecosystem2026-05-10 收录

DNA损伤修复

DNA复合物

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Dpo4 DNA polymerase (R336A) in complex with DNA containing an 8oxoG template lesion

创建时间：

2025-10-08

Effect of DNA break-induced transcriptional repression on genome stability. Homo sapiens

DNA损伤修复

染色质调控

Cohesin and the PBAF chromatin remodelling complex are required to repress transcription at sites of DNA double strand breaks. To investigate this and rule out known sister-chromatid dependent functio

NIAID Data Ecosystem60

Structure of BstEII with DNA substrate

DNA复合物

限制性内切酶

Structure of BstEII with DNA substrate

NIAID Data Ecosystem50

Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients.

皮肤癌突变谱

DNA损伤修复

The UV component of sunlight is the major carcinogen involved in the etiology of skin cancers. We have studied the rare, hereditary syndrome xeroderma pigmentosum (XP), which is characterized by a ver

PubMed Central1993-11-15 更新40

SERENDIPITOUS CRYSTAL STRUCTURE CONTAINING THE HEAT SHOCK TRANSCRIPTION FACTOR'S DNA BINDING DOMAIN AND COGNATE DNA THAT IS TRANSLATIONALLY DISORDERED

DNA复合物

转录因子机制

SERENDIPITOUS CRYSTAL STRUCTURE CONTAINING THE HEAT SHOCK TRANSCRIPTION FACTOR'S DNA BINDING DOMAIN AND COGNATE DNA THAT IS TRANSLATIONALLY DISORDERED Descriptor: HEAT SHOCK FACTOR PROTEIN, HSE DNA-PH

Protein Data Bank Japan2024-11-20 更新50

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

Dpo4 DNA polymerase (R336A) in complex with DNA containing an 8oxoG template lesion

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