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Myeloid cell specific deletion of AMPK alpha worsens ocular bacterial infection

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP524046
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资源简介:
The eye is highly susceptible to inflammation-mediated tissue damage evoked during bacterial infection. AMP-activated protein kinase (AMPK) plays a crucial role in governing essential cellular functions such as growth, proliferation, and survival. Here, we investigated the specific involvement of AMPK alpha 1 in myeloid cells. Overall, our study underscores the role of myeloid-specific AMPK alpha 1 in promoting the resolution of inflammation in the eye during bacterial infection.
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2025-07-02
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