CYP2C19 is one of the most important drug metabolizing enzymes in human body. The gene base is located in chromosome region 10q 24.2 and consists of 9 exons. CYP2C19 has many single nucleotide polymor
Nucleotide variations in bold are the major SNPs/alterations responsible for the phenotype of the corresponding allele.Nucleotide and amino acid variations underlined are novel and have not been repor
The Keap1/Nrf2 signaling pathway is a tractable target for the pharmacological prevention of tumorigenesis. 3H-1,2-dithiole-3-thione (D3T) and 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole
Medication safety and efficacy-related pharmacogenomic research play a critical role in precision medicine. This study comprehensively analyzed the pharmacogenomic profiles of the central Han Chinese