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A Novel, Efficient, Diastereo- and Enantioselective Mukaiyama Aldol-Based Synthesis of a Vinyl Cyclopentanone Core Derivative of Viridenomycin

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/A_Novel_Efficient_Diastereo_and_Enantioselective_Mukaiyama_Aldol_Based_Synthesis_of_a_Vinyl_Cyclopentanone_Core_Derivative_of_Viridenomycin/2968054
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A strategy has been developed for a rapid seven-step construction of a chiral, nonracemic vinyl cyclopentanone building block as part of a synthetic approach to viridenomycin, using a diastereo- and enantioselective Mukaiyama aldol and intramolecular Knoevenagel condensation as key steps.
创建时间:
2016-06-03
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