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ChIP-sequencing of histone marks in WT and Fmr1-/- (KO) neurons and mice

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NIAID Data Ecosystem2026-03-12 收录
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Widespread misregulation of histone modifcations occur in FXS, most notably increases in marks associated with active transcription. Overall design: 7DIV cultured cortical neurons from WT or Fmr1 KO mice were processed for H3K4me3 and H3K27ac ChIP. In addition, neurons sorted from cerebellar tissue from WT and Fmr1 KO BAC-TRAP NeuroD1 P15 mice were used for H3K4me3 ChIP, performed in triplicate

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2021-07-25
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