human metagenome Raw sequence reads. human metagenome

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths worldwide. Although dysbiosis of lung and gut microbiota have been associated with NSCLC, their relative contributions are unclear; in addition, their roles in distant metastasis (DM) are still illusive. We conducted a comprehensive survey on both fecal and sputum (as a proxy for lung) microbiota in NSCLC patients of various stages, including stage Ⅳ patients suffered from distant metastasis (DM), and compared them with healthy controls of matching demographic and clinical characteristics.