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The m6A Reader IGF2BP2 Regulates Glutamine Metabolism and Represents a Therapeutic Target in Acute Myeloid Leukemia [Ribo-seq]

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NIAID Data Ecosystem2026-03-14 收录
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We report that m6A reader IGF2BP2 participates in the regulation of glutamine metabolism in AML. To further clarify whether IGF2BP2 knockdown (KD) leads to translational inhibition, we perform Ribo-seq in control and IGF2BP2 KD cells. Overall design: MM6 cells infected with shNS or shIGF2BP2 (including shBP2B and shBP2D) were employed for ribo-seq.

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2022-11-02
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