The SARS-CoV-2-perturbed network.
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https://www.ndexbio.org/viewer/networks/25708de8-f1b1-11ea-99da-0ac135e8bacf
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The SARS-CoV-2-perturbed host cellular network in response to different viral loads in A549 cells. The network comprises 130 nodes and 305 edges (including 155 basal edges). The colored solid edges represent the SARS-CoV-2-perturbated differentially regulated edges (DREs); high MOI of 2 (magenta), low MOI of 0.2 (blue), high MOI ∩ low MOI (purple). Dot edges represent the basal edges (grey). The nodes (green) represents the known drug target genes (See the paper: Supplementary Table S1). The node size stands for the extent of outdegree. In the Table, sample-labeled columns represent the relative contribution value (RC) for each sample. These labels correspond to the original dataset. The Bayesian network estimation was peformed using the publically available RNA-seq dataset (GSE147507). The detailed methods are described in the paper.
创建时间：
2020-09-09
