Additional file 2: of Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes

Figure S1. Effect of siRNAs or DNA expression plasmids transfections in C-MSCs. Figure S2. MSCs cultured on 2D plastic culture plate maintained YAP/TAZ activity. Figure S3. High YAP/TAZ activity in subconfluent MSCs cultured on a 2D plastic plate regulates the cell lineage into osteogenesis but not adipo/chondrogenesis. Figure S4. Disruption of F-actin integrity by ROCK inhibitor and acto-myosin inhibitor abrogates the TAZS89A-induced positive feedback loop for in C-MSCs. (ZIP 6647 kb)