High-resolution reconstruction of the insect peripheral nervous system
收藏ESRF Portal2028-01-01 更新2026-04-23 收录
下载链接：
https://doi.esrf.fr/10.15151/ESRF-ES-2156223187
下载链接
链接失效反馈官方服务：
资源简介：
Animals interact with the world by coordinating the movement of left-right pairs of limbs. Typically, each pair of limbs evolved different anatomy to perform complementary functions. The nervous system has likewise evolved distinct neural circuits to control limbs with different anatomy. How are limb anatomical specializations represented at the level of synaptic connections between neurons? The fruit fly, Drosophila melanogaster, is an emerging model for understanding the neural circuits that control locomotion. Here, we propose to image the external and internal anatomy of a fly’s middle and hind legs at ~100 nm resolution to complement our X-ray tomographic volume of a fly’s front leg (project LS-2845, Kuan et al. 2020, Nature Neuroscience, Azevedo et al. 2024, Nature). The resulting anatomical detail will allow us to relate quantitative comparisons of neural circuit connectivity to neuromechanical specializations of the legs.
提供机构：
University of Washington, Physiology and Biophysics Department, 1705 NE Pacific Street, Hsb Room G424, Box 357290, 98195-7290 Seattle, Usa
创建时间：
2028-01-01
