Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378
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Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378 Descriptor: ALK tyrosine kinase receptor, GLYCEROL, N~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine Authors: Lee, C.C, Spraggon, G. Deposit date: 2015-04-02 Release date: 2016-02-03 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
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2015-04-02
