VNS and seizure outcomes in pediatric refractory epilepsy: Systematic review and meta-analysis

This data provides supplemental information for the systematic review and Meta-analysis. Supplemental tables report the detailed serach strategy (Supplementary Table 1), details of included studies (Supplementary Table 2), list of excluded studies (Supplementary Table 3), 50% Responder Rate in children with Lennox-Gastaut syndrome after VNS insertion (Supplementary Table 4), 50% Responder Rate in children with Dravet syndrome after VNS insertion (Supplementary Table 5), VNS settings and other seizure outcomes reported in the included studies (Supplementary Table 6) and Studies reporting a formal Quality of life (QOL) assessment in children post VNS implantation (Supplementary Table 7).

Supplemental figure 1 (S1) shows the PRISMA flowchart for this systematic review. 

Supplemental Figure 2 (S2): Determinants of Seizure Outcomes. Multivariable regression showed 50%-RR at last reported follow-up to increase with increasing age of onset of seizures and decrease with the number of ASM...