PTIR1 acts as a suppressor of immunoproteasome and promotes cancer immune resistance [TILs 10x scRNA-seq]. PTIR1 acts as a suppressor of immunoproteasome and promotes cancer immune resistance [TILs 10x scRNA-seq]
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA823649
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资源简介：
Cancer cells evade host immune surveillance by virtue of poor immunogenicity. We identify a novel oncogene that acts as a promotor of tumor immune resistance, designated as PTIR1. Tumor-intrinsic PTIR1 is induced by RNA splicing and highly correlated with poor outcome of patients with cancer. Overall design: Study of tumor infiltration lymphocytes in colon cancers with or without PTIR1 expressing using 10x scRNA-seq technologies.
创建时间：
2022-04-05
