Overexpression of DDX42 suppresses the altered RNA splicing associated with the K700E mutated SF3B1 in 293T cells. Overexpression of DDX42 suppresses the altered RNA splicing associated with the K700E mutated SF3B1 in 293T cells

We report the bulk RNA-seq in HEK293T cells transfected with DExD/H ATPase and SF3B1 Overall design: RNA-seq in wild type SF3B1 transfected 293T cells (WT); SF3B1-K700E mutation transfected 293T cells (K700E); 293T cells transfected with SF3B1-K700E and DDX42 (K700E&DDX42); 293T cells transfected with SF3B1-K700E and DDX46 (K700E&DDX46). Each cell type have 5 biological replicates.