A Convenient Protocol for the Synthesis of Ligands from a 4-Methyl-3,5-diacylaminophenyl Platform

The synthesis of stable and highly organized phenanthroline, terpyridine, and pyridino-oxazoline
ligands bearing one or two 4-methyl-3,5-diacylaminophenyl modules equipped with two lateral
dialkoxyphenyl groups has been performed using EDC·HCl and DMAP reagents in the final coupling
reaction. Evidently, in the final ligands and in the solid state intermolecular hydrogen bonding
maintains the coherence of the tridimensional structure as clearly evidenced by FT-IR and X-ray
diffraction spectroscopy in the cases of the methoxy ligands. The supramolecular packing is also
maintained by additional π−π stacking interactions.