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Lactic Acid as an Epigenetic Metabolite in Glioblastoma

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE145699
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We investigate the role of lactic acid in GBM cells as an epigenetic metabolite in the regulation of pro-survival gene expression. KNS42, GBM22 and GBM43 cells were starved (0.5mM Glucose; 0.5mM Glutamate media) for 24h with or without L-lactic acid for 24h. Thereafter, cells were harvested and subjected to RNA extraction and submitted for microarray analysis.
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2022-08-31
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