Skeletal-muscle metabolic reprogramming in ALS-SOD1G93A mice
收藏NIAID Data Ecosystem2026-03-11 收录
官方服务：
资源简介：
Identify altered molecular markers in skeletal muscle during ALS progression
应用场景：
创建时间：
2020-04-07
相关数据集
Expression data of iPSC-derived motor neurons from healthy donor, FALS, SALS, and drug-treated them
We established several iPSCs from healthy donors, familial ALS (FALS) patients, and sporadic ALS (SALS) patients. Using our differentiation protocol originally developed, we differentiated these iPSCs
NIAID Data Ecosystem30
Raw and analyzed data_Soll et al 2021
In this study we used the SOD1 G93R mutant zebrafish ALS model to assess whether 1-Fe, as a potent catalytic antioxidant, displays any therapeutic merits in vivo. Our results show that 1-Fe caused a s
Figshare2021-05-20 更新20
RNAseq of oculomotor (OMN) and spinal motor neurons (SC) derived from mouse embryonic stem cells and purified by FACS. RNAseq of oculomotor (OMN) and spinal motor neurons (SC) derived from mouse embryonic stem cells and purified by FACS
Oculomotor neurons, which regulate eye movement, are resilient to degeneration in the lethal motor neuron disease amyotrophic lateral sclerosis (ALS). It would be highly advantageous if motor neuron r
NIAID Data Ecosystem20
A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model
A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model Descriptor: (3E)-6,7-dichloro-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-one, CALCIUM
Protein Data Bank Japan2024-03-13 更新30
Sex-Dependent Changes to the Intestinal and Hepatic Abundance of Drug Transporters and Metabolizing Enzymes in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is characterized by death and dysfunction of motor neurons that result in a rapidly progressing loss of motor function. While there are some data on alterations at
NIAID Data Ecosystem20
