RNA-Seq shows that HAVCR1 knockdown does not affect JEG3 interferon signaling response

To investigate whether HAVCR1 knockout (KO) affects the response of the interferon signaling pathway in JEG3 cells, RNA-Seq was performed on HAVCR1 KO and control JEG3 cells under both basal conditions and stimulation with double-stranded RNA mimic poly I:C. The results indicated that HAVCR1 knockdown does not affect the interferon signaling pathway response in JEG3 cells. Both groups exhibited comparable activation of the interferon signaling pathway. The experimental design involves comparing HAVCR1 knockout (KO) JEG3 cells and control JEG3 cells under two conditions: basal conditions and stimulation with the double-stranded RNA mimic poly I:C