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Highly Efficient Synthesis of the Tricyclic Core of Taxol by Cascade Metathesis

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NIAID Data Ecosystem2026-03-08 收录
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https://figshare.com/articles/dataset/Highly_Efficient_Synthesis_of_the_Tricyclic_Core_of_Taxol_by_Cascade_Metathesis/2281138
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资源简介:
An efficient enantioselective synthesis of the ABC tricyclic core of the anticancer drug Taxol is reported. The key step of this synthesis is a cascade metathesis reaction, which leads in one operation to the required tricycle if appropriate fine-tuning of the dienyne precursor is performed.
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2014-06-20
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