Retrieval counts by the various methods on new kinase targets (a) PknB, (b) BGLF4, and (c) ROP18 using PKIS1 or PKIS2 matrices.

The total number of experimentally determined active compounds and distinct active scaffolds is indicated in the total column. The values below each of the IBR methods indicate the number of active informers identified, the number of experimentally determined active compounds that were ranked in the top 10% of predicted active compounds by each method, and the number of unique active scaffolds identified in those top 10%. For a given target, these 10% are the active informers and the top ranking non-informers comprising 10% of the set of all compounds after removing inactive informers.