PDE2 catalytic domain complexed with inhibitors
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PDE2 catalytic domain complexed with inhibitors Descriptor: (3R)-1-{3-[5-(4-ethylphenyl)-1-methyl-1H-pyrazol-4-yl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-N,N-dimethylpyrrolidin-3-amine, MAGNESIUM ION, ZINC ION, ... Authors: Pandit, J, Parris, K. Deposit date: 2016-12-12 Release date: 2017-06-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor. J. Med. Chem., 60, 2017
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2016-12-12
