Transcription profiling of mouse at ages P4 and P60 in sciatic nerve of wild type and with peripheral neuropathies to study disease mechanisms in peripheral neuropathies due to altered Pmp22 gene dosage or a Pmp22 point mutation

We compared gene expression at ages P4 and P60 in sciatic nerve of wild type mice and mice with peripheral neuropathies caused by altered Pmp22 gene dosage (homozygous knockout or transgene) or a point mutation (Trembler).本研究对野生型小鼠，以及因Pmp22基因剂量改变（纯合敲除或转基因）或点突变（震颤（Trembler））引发周围神经病的小鼠，在P4与P60日龄时的坐骨神经基因表达水平进行了对比分析。