Relevant characteristics of S. pneumoniae isolates and their prophages analyzed in this study.

aClones are named by their clonal complex number. Those showed in boldface and underlined are the main clones involved in Fq resistance in Spain since 2002.bIsolates are separated on the basis of their Fq susceptibility: S, susceptible (CPX MICs ≤2 mg/L); R, resistant (MICs ≥4 mg/L).cPCR detection for hol1 gene.dFunctional phages caused cell lysis in the presence of MitC.