Open TG-GATEs

Open TG-GATEs是一个毒物基因组学数据库，由毒物基因组学项目(TGP)及其后续项目(TGP2)创建。该数据库包含170种化合物的基因表达数据，这些数据通过大鼠或大鼠和人类原代培养肝细胞的实验获得，并对肝脏和肾脏中的基因表达谱进行了微阵列分析。研究人员可以通过化合物名称或病理发现搜索毒物基因组学数据，并下载与表型数据相关的基因表达数据(CEL文件)。Open TG-GATEs is a toxicogenomics database developed by the Toxicogenomics Project (TGP) and its follow-up project TGP2. This database contains gene expression data for 170 compounds, which were generated via experiments using rat, or both rat and human primary cultured hepatocytes, with microarray analysis conducted on gene expression profiles in the liver and kidney. Researchers can search toxicogenomics data by compound name or pathological findings, and download gene expression data (CEL files) associated with phenotypic data.