Castration-resistant prostate cancer (CRPC) marks the advanced and lethal stage of prostate cancer (PCa). TRIM28, also known as KAP1, is a transcriptional regulator recently shown to promote CRPC cell
Functional annotation clustering of genes with a H3K27ac differently enriched promoter connected to transcription factors with motifs overrepresented in soleus and EDL myonuclei, respectively. Cluster
i. rate has only been measured for 1,25(OH)2D [50].ii. Kr1 = 500*Kr2.iii. Kr2 = 1/Kd where Kd = 1×10−10[42].iv. Kcat*YT = 0.1 µM/hr [46].v. estimate based on [29], [47], [48], [49].vi. 3000 molecules/
In each of the three sub-challenges the number of nodes was held constant but the number of edges and regulator nodes was not. There were five gold standard networks in each of the three sub-challenge
