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Chronic hypoxia favours adoption to a castration-resistant cell state in prostate cancer

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NIAID Data Ecosystem2026-05-01 收录
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Hypoxia is associated with poor prognosis in solid tumours and hypoxia has been associated with prostate cancer progression. The investigation of how chronic (CH) hypoxia affected prostate cancer show a loss in sensitivity to androgen deprivation and increased dependancy on glucose uptake in cells. Overall design: Comparative gene expression profiling of LNCaPs to LNCaP-CH and LNCaP to LNCaP-V16A cell lines

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2023-07-07
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