首页/数据集/Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine

Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine

NIAID Data Ecosystem2026-05-02 收录

内分泌调控

成瘾性别差异

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE229696 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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创建时间：

2025-02-04

内分泌调控

生殖激素互作

Introduction: Two common responses to stress include elevated circulating glucocorticoids and impaired luteinizing hormone (LH) secretion. We have previously shown that a chronic stress level of corti

NIAID Data Ecosystem50

Genome-wide RNAseq of hippocampi from single time point (2 hours post 0.75 mg/mL corticosterone injection) in adrenalectomized rats

内分泌调控

海马体研究

Disrupted circadian activity is associated with many neuropsychiatric disorders. A major coordinator of circadian biological systems is adrenal glucocorticoid secretion which exhibits a pronounced pre

NIAID Data Ecosystem20

Supplementary Material for: Nuclear Receptor Coactivators Are Coexpressed with Steroid Receptors and Regulated by Estradiol in Mouse Brain

内分泌调控

类固醇信号传导

Background/Aims: The steroid hormones, including estradiol (E) and progesterone, act in the brain to regulate female reproductive behavior and physiology. These hormones mediate many of their biologic

Figshare2017-06-20 更新20

Deletion of adrenocortical Bmal1 results in sex-biased gene expression.

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生物钟蛋白功能

We report that deletion of BMAL1 from adrenocortical cells using a SCC(Cyp11a1)-Cre driver reults in elevated plasma corticosterone in female, but not in male mice, following submaximal stress stimula

NIAID Data Ecosystem30

Loss of brain insulin production impairs learning and memory in female mice

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内分泌调控

Diabetes is a metabolic disorder characterized by dysfunctional insulin release and action, and it is a risk factor for Alzheimer's disease, the most common form of dementia. Alterations in brain insu

NIAID Data Ecosystem20

Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine

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