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Engineered cardiac microbundle time-lapse microscopy image dataset

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DataCite Commons2025-06-01 更新2025-04-09 收录
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https://datadryad.org/dataset/doi:10.5061/dryad.5x69p8d8g
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资源简介:
The "Microbundle Time-lapse Dataset" contains 24 experimental time-lapse images of cardiac microbundles using three distinct types of experimental testbeds. Of the 24 experimental time-lapse images, 23 examples are brightfield videos, and a single example is a phase contrast video. We categorize the different experimental testbeds into 3 types, where "Type 1" includes movies obtained from standard experimental microbundle platforms termed microbundle strain gauges [1,2,3]. We refer to data collected from non-standard platforms termed FibroTUGs [4] as "Type 2" data, and "Type 3" data represents a highly versatile and diverse nanofabricated experimental platform [5,6]. References: [1] Boudou T, Legant WR, Mu A, Borochin MA, Thavandiran N, Radisic M, Zandstra PW, Epstein JA, Margulies KB, Chen CS. A microfabricated platform to measure and manipulate the mechanics of engineered cardiac microtissues. Tissue Engineering Part A. 2012 May 1;18(9-10):910-9. [2] Xu F, Zhao R, Liu AS, Metz T, Shi Y, Bose P, Reich DH. A microfabricated magnetic actuation device for mechanical conditioning of arrays of 3D microtissues. Lab on a Chip. 2015;15(11):2496-503. [3] Bielawski KS, Leonard A, Bhandari S, Murry CE, Sniadecki NJ. Real-time force and frequency analysis of engineered human heart tissue derived from induced pluripotent stem cells using magnetic sensing. Tissue Engineering Part C: Methods. 2016 Oct 1;22(10):932-40. [4] DePalma SJ, Davidson CD, Stis AE, Helms AS, Baker BM. Microenvironmental determinants of organized iPSC-cardiomyocyte tissues on synthetic fibrous matrices. Biomaterials science. 2021;9(1):93-107. [5] Jayne RK, Karakan MÇ, Zhang K, Pierce N, Michas C, Bishop DJ, Chen CS, Ekinci KL, White AE. Direct laser writing for cardiac tissue engineering: a microfluidic heart on a chip with integrated transducers. Lab on a Chip. 2021;21(9):1724-37. [6] Karakan MÇ. A Direct-Laser-Written Heart-on-a-Chip Platform for Generation and Stimulation of Engineered Heart Tissues (Doctoral dissertation, Boston University, 2023).
提供机构:
Dryad
创建时间:
2023-08-07
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