Syk kinase domain in complex with macrocyclic inhibitor 20a
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Syk kinase domain in complex with macrocyclic inhibitor 20a Descriptor: 10,13,23-trimethyl-16-oxa-2,4,8,9,13,19,23,30-octazapentacyclo[19.5.2.1^{3,7}.1^{8,11}.0^{24,28}]triaconta-1(27),3,5,7(30),9,11(29),21,24(28),25-nonaen-20-one, Tyrosine-protein kinase SYK Authors: Read, J.A, Patel, J. Deposit date: 2022-11-01 Release date: 2023-06-14 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.508 Å) Cite: Optimization of a series of novel, potent and selective Macrocyclic SYK inhibitors. Bioorg.Med.Chem.Lett., 91, 2023
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2022-11-01
