Full length structure of the apo-state LpMIP. Descriptor: (1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-(hydroxymethyl)-3-[(1~{S})-1-pyridin-2-ylethyl]-3,10-diazabicyclo[4.3.1]decan-2-on
MDMs or PMA-differentiated THP-1 were incubated for 60 minutes with strains at an MOI of 10. The significance of differences between the mutant and the WT strain was evaluated: *, p<0.05; **, p<0.01;
The Type 3 Secretion System encoded by the Salmonella pathogenicity island 2 (SPI-2 T3SS) enables bacterial proliferation in Salmonella-containing vacuole and dissemination throughout the host. Despit