Additional file 6: Table S5. Quantifications of intronic polyadenylation related counts from RNA-sequencing upon treatment with THZ531, lapatinib, nilotinib and combinations in Hs578T.
Acute myeloid leukemia (AML) is a malignant hematopoietic disease with poor prognosis for most patients. Conventional chemotherapy has been the standard treatment approach for AML in the past 40 years
The combination index (CI) values were calculated using the Chou and Talalay mathematical model for drug interaction on Calcusyn software. A CI was equal to 1 denotes additivity; antagonism if the CI>
