neuroendocrine control of planarian regeneration

Effective tissue regeneration requires cells to perceive the surrounding context and make internal state adaptations that enable context-dependent fate changes in time and space, but the mechanisms underlying this complex process remain unclear. Here, transcriptom sequencing was used for study neuroendocrine control of planarian regneration Overall design: Examine gene expression profiles of 10dpf adult planarian after EGFP RNAi(control) and nsf RNAi.