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Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST

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Protein Data Bank Japan2024-02-07 更新2026-04-19 收录
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Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST Descriptor: 5-imidazo[1,2-a]pyridin-3-yl-~{N}-[(1~{R})-1-(6-pyrrolidin-1-ylpyridin-3-yl)ethyl]pyridin-3-amine, HUMAN PROTO-ONCOGENE C-KIT Authors: Graedler, U, Lammens, A. Deposit date: 2022-05-24 Release date: 2023-02-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.09 Å) Cite: Identification of M4205─A Highly Selective Inhibitor of KIT Mutations for Treatment of Unresectable Metastatic or Recurrent Gastrointestinal Stromal Tumors. J.Med.Chem., 66, 2023
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2022-05-24
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