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Copper-Mediated Oxidative Coupling of Benzamides with Maleimides via Directed C–H Cleavage

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NIAID Data Ecosystem2026-03-08 收录
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https://figshare.com/articles/dataset/Copper_Mediated_Oxidative_Coupling_of_Benzamides_with_Maleimides_via_Directed_C_H_Cleavage/2139061
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资源简介:
A Cu­(OAc)2/Cy2NMe-mediated oxidative direct coupling of benzamides with maleimides has been developed. The aromatic C–H alkenylation with the aid of an 8-aminoquinoline-based bidentate directing group is followed by an intramolecular aza-Michael-type addition to form the isoindolone-incorporated spirosuccinimides, which are of potent interest in medicinal chemistry.
创建时间:
2016-02-13
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