Cross-Species Comparisons of Toxicokinetic Parameters to Evaluate In Vitro-In Vivo Correlation Performance for Commercial Chemicals
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下载链接：
https://epa.figshare.com/articles/dataset/Cross-Species_Comparisons_of_Toxicokinetic_Parameters_to_Evaluate_In_Vitro-In_Vivo_Correlation_Performance_for_Commercial_Chemicals/28912634
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资源简介：
This study generated rat in vivo toxicokinetic data to derive bioavailability information for chemicals of interest to Agency program office partners. The data will be used in conjunction with in vitro TK data to evaluate factors that modulate bioavailability; and to more generally evaluate the role of species differences on in vitro-in vivo concordance and in vitro in vivo extrapolation performance. Such evaluations are important in identifying next steps needed to improve TK New Approach Methods.Search for CCTE records in EPA’s Science Inventory by typing in the title at this link:https://cfpub.epa.gov/si/si_public_search_results.cfm?advSearch=true&showCriteria=2&keyword=CCTE&TIMSType=&TIMSSubTypeID=&epaNumber=&ombCat=Any&dateBeginPublishedPresented=07/01/2017&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&DEID=&personName=&personID=&role=Any&journalName=&journalID=&publisherName=&publisherID=&sortBy=pubDate&count=25
提供机构：
The United States Environmental Protection Agency’s Center for Computational Toxicology and Exposure
创建时间：
2025-05-01
