CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH COMPOUND1
收藏Protein Data Bank Japan2025-12-24 更新2026-04-19 收录
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CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH COMPOUND1 Descriptor: 2-(3,4-dimethoxyphenyl)-3,5-bis(oxidanylidene)-4-[[3-(trifluoromethyl)phenyl]methyl]-1,2,4-triazine-6-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chymase, ... Authors: Schaefer, M, Fuerstner, C, Ackerstaff, J, Meier, H, Straub, A, Mittendorf, J, Schamberger, J, Boerngen, K, Joerissen, H, Zubow, D, Zimmermann, K, Tersteegen, A, Geiss, V, Hartmann, E, Albrecht-Kuepper, B, Dorleans-Juste, P, Lapointe, C, Vincent, L, Heitmeier, S, Tinel, H. Deposit date: 2024-07-31 Release date: 2024-11-27 Last modified: 2025-12-24 Method: X-RAY DIFFRACTION (2.375 Å) Cite: Discovery and Preclinical Characterization of Fulacimstat (BAY 1142524), a Potent and Selective Chymase Inhibitor As a New Profibrinolytic Approach for Safe Thrombus Resolution. J.Med.Chem., 68, 2025
创建时间：
2024-07-31
