IFN gamma signaling in cytotoxic T cells restricts antitumor responses by inhibiting the maintenance and clonality of intra-tumoral stem-like T cells
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资源简介：
IFN gamma signaling in cytotoxic T cells restricts antitumor responses by inhibiting the maintenance and clonality of intra-tumoral stem-like T cells C57Bl6 WT mice and CD8-IFNgRKO mice were engrafted with the melanoma cell line B16 expressing OVA. CD3+ CD8+ T cells were isolated by Fluorescence-activated cell sorting (FACS) from the tumor and draining lymph node after 12 days and subjected to scRNA and scTCR sequencing.
创建时间：
2023-02-06
