Leopard Frog PFOS & PFHxS Mixture Study
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https://purr.purdue.edu/publications/4119/1
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资源简介：
<p>PFAS at aqueous film forming foam (AFFF) impacted sites occur as mixtures, with perfluorooctanesulfonic acid (PFOS) and perfluorohexanesulfonic acid (PFHxS) most commonly co-occurring in the highest concentrations. Although PFOS and PFHxS toxicities have been studied extensively, few studies have tested potential interactions between the two. This study compared toxicities of a 1:1 PFOS:PFHxS mixture to PFOS and PFHxS individually with the prediction that responses would be additive. Leopard frog tadpoles were exposed to either 0.5 ppb or 1 ppb PFOS or PFHxS singly or a mixture of 0.5 ppb PFOS and 0.5 ppb PFHxS throughout metamorphosis (GS 25 through GS 46).&nbsp; Survival was monitored throughout the study.&nbsp; Phenotypic responses (mass, SVL, SMI) were measured at day 31, GS 42 (metamorphic climax), and GS 46 (completion of metamorphosis).&nbsp; PFAS body burdens were measured at day 31 of exposure and at GS 46, BCFs were calculated at GS 46.&nbsp;&nbsp;</p>
提供机构：
Purdue University Research Repository
创建时间：
2022-08-02
