Enantioselective Spirocyclopropanation of <i>para</i>-Quinone Methides Using Ammonium Ylides
收藏NIAID Data Ecosystem2026-03-10 收录
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The use of Cinchona alkaloid-based chiral ammonium ylides allows for the first highly enantioselective and broadly applicable spirocyclopropanation reactions of para-quinone methides. This strategy provides a straightforward protocol toward the chiral spiro[2.5]octa-4,7-dien-6-one skeleton, which is a frequently found structural motif in important biologically active molecules.
创建时间:
2017-04-20



