The data underlying Fig 7.

(A) Supplementation of growth media with sphingoid bases protected cells from cpoS mutant-induced death. Host cell viability based on nuclei count was measured 25.5 hrs post infection and treatment with the indicated bacterial strains and metabolites. Data are displayed in Fig 7A. (B) Supplementation of growth media with sphingoid bases restored the growth of the cpoS mutant. Bacterial growth based on inclusion count was measured 25.5 hrs post infection and treatment with the indicated bacterial strains and metabolites. Data are displayed in Fig 7B. (C) Stabilizing effect of sphingosine on CpoS-deficient inclusions. GFP10-expressing HeLa cells were infected with the indicated strains and parallelly treated with 5 µM sphingosine (Sph) or left untreated (control). Cells were fixed, stained, and imaged at 24 hpi. The percentage of infected cells, surviving cells, and infected cells containing cytosolic bacteria was determined by manual image analysis. Data are displayed in Fig 7C. (XLSX)