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Transcriptomic profiling of bone marrow stromal cell subsets during chronic viral infection with LCMV

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NIAID Data Ecosystem2026-03-13 收录
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RNA sequencing of two stromal cell subsets of the bone marrow, namely CXCL12-abundant reticular cells (CARc) and sinusoidal endothelial cells (SECs) isolated from untreated mice (day 0) and mice infected with Lymphocytic Choriomeningitis Virus cl-13, 56 days after infection (day 56) Overall design: RNA-sequencing of two FACS-sorted mouse bone marrow stromal cells based on phenotypic marker expression from uninfected control (day 0) and LCMV-cl13 infected mice (56 day post infection-day 56). Cell subsets were sorted according to previously defined phenotypic signatres. CARc; CD45-Ter119-Cd31-CD140b+Sca-1- . SECs; CD45-Ter119-CD31+Sca-1+CD105hi

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2021-12-21
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