Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition
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Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition Descriptor: N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S,3S)-3-hydroxy-1-(4-hydroxyphenyl)-4-oxobutan-2-yl]-L-leucinamide, Proteasome component C1, Proteasome component C11, ... Authors: Groll, M, Poynor, M, Gallastegui, P, Stein, M, Schmidt, B, Kloetzel, P.M, Huber, R. Deposit date: 2010-08-25 Release date: 2011-06-08 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Elucidation of the alpha-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition Angew.Chem.Int.Ed.Engl., 50, 2011
创建时间:
2010-08-25



