Pseudoknot RNA degraders – directed and irreversible degradation of SARS-CoV-2 genome as an antiviral strategy
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE182826
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We demonstrate that the pseudoknot binder MTDB selectively degrades coronaviral pseudoknots in vitro, in cells and in a SARS-CoV-2 infection mouse model, which means it has great potential to be used as an anti-SARS-CoV-2 therapeutic. Oxford Nanopore sequencing of SARS-CoV-2 RNA
创建时间：
2024-11-05
