CRCbiome metagenomes. CRCbiome

The overall aim om the CRCbiome study is to discover gut microbiota biomarkers for colorectal cancer screening. To reach the overall aim we have defined the following sub-aims: Identify associations of the gut microbiome with advanced neoplasia, defined as presence of advanced adenoma or CRC Examine interactions of the gut microbiome with host factors, diet, lifestyle and medication use on advanced neoplasia risk Describe modifications of the gut microbiome following removal of precursor lesions of CRC The project is establishing a cohort including including a biobank with fecal samples and biopsies, lifestyle information and data from national health registries for use in future studies.