3D Chromosome Structure Can Reveal Stem Cell Signatures (RNA-Seq)

NIAID Data Ecosystem2026-04-30 收录

染色质三维结构分析

细胞表观基因组学

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP183173 数据链接链接失效反馈

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资源简介：

We use in situ Hi-C to report the most comprehensive survey to date of chromatin organization in stem cells Overall design: 2 cell types

创建时间：

2022-01-21

Mint-ChIP-seq from effector memory CD8-positive, alpha-beta T cell (ENCSR707ZDY)

效应记忆T细胞ChIP-seq

细胞表观基因组学

For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf https://www.e

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Subtle changes in chromatin loop contact propensity are associated with differential gene regulation and expression. Subtle changes in chromatin loop contact propensity are associated with differential gene regulation and expression

染色质三维结构分析

基因表达调控

We quantitatively interrogate these relationships by comparing Hi-C and molecular phenotype data across cell types and haplotypes. While chromatin loops consistently form across different cell types,

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DNase-seq from CD4-positive, alpha-beta T cell (ENCSR126EVX)

染色质可及性分析

细胞表观基因组学

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Targeted in situ genome-wide profiling with high efficiency for low cell numbers

染色质靶向分析

细胞表观基因组学

Cleavage Under Targets and Release Using Nuclease (CUT&RUN) is an epigenomic profiling strategy in which antibody-targeted controlled cleavage by micrococcal nuclease releases specific protein-DNA com

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5C with wild type mESC, wild type NPC and mESC with various PcG components knocked-out

染色质三维结构分析

表观遗传调控

Master regulatory genes require stable silencing by the Polycomb-Group (PcG) to prevent improper expression during differentiation and development. Some PcG proteins covalently modify histones, which

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3D Chromosome Structure Can Reveal Stem Cell Signatures (RNA-Seq)

资源简介：

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