Gut microbiota analysis in poorly controlled diabetes patients with latent TB infection (LTBI) and nonLTBI [16S rRNA]

In previous study, patients with Diabetes Mellitus (DM) have high risk of active TB and LTBI. Here we report and compare 16S rRNA data of DM-LTBI and DM-nonLTBI in gut microbiota to identify differential candidates between the two groups. The results showed the differential genera have potential to predict the LTBI status in patients. Microbial DNA from fecal samples including two groups, DM with LTBI (n=43) and non-LTBI (n=87), were amplified by PCR using V3-V4 primers of bacteria.