DNA methylation profiling of lung transplant recipients

Targeted bisulfite sequencing data of peripheral blood mononuclear cells (PBMCs) from participants pre- and post- lung transplant(Tx) was generated to study 1) methylation difference between pre- and postTx, 2) methylation difference between cytomegalovirus (CMV) seropositive and seronegative in preTx, and 3) immune response regarding Tx and immunosuppression prophylaxes. Overall design: We collected PBMC for targeted bisulfite sequencing from 135 kidney transplant patients with samples collected before and then 3 months after transplantation.